INTRODUCTION: Seizures are short bursts of spontaneous movement that might affect either a portion of the body (partial) or the entire body (generalized), and they can occasionally be followed by a loss of consciousness and control over bowel or bladder function. Around 50 million people worldwide suffer from epilepsy, a chronic, noncommunicable brain condition Excessive electrical discharges in a cluster of brain cells cause seizure episodes. Such discharges can occur in many areas of the brain. The smallest muscular twitches or concentration lapses can be seizures, as can violent convulsions that last for a long time. The frequency of seizures…
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Introduction The Ebola virus, a powerful pathogen from the family Filoviridae, is well-known for being the pathogenic agent that causes Ebola Virus Disease (EVD). The Ebola River, which is close to the outbreak’s beginning, inspired the name of the disease, which was first discovered in 1976 amid outbreaks in Sudan and the Democratic Republic of the Congo. The fast and sometimes deadly course of EVD, which is characterized by symptoms including fever, muscular discomfort, vomiting, and bleeding, is what makes it distinctive. It is thought that this zoonotic virus spreads to people when they come into contact with infected animals,…
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Introduction The hereditary disorder Duchenne muscular dystrophy (DMD), which predominantly affects the muscles and causes muscle weakness and eventually loss of muscle function, is severe and progressive. It is one of the most prevalent and disabling types of muscular dystrophy, generally detected in young boys. DMD is named for the 19th-century French neurologist Guillaume Duchenne, who initially identified the disorder. Mutations in the DMD gene, which is found on the X chromosome and encodes the protein dystrophin, which is crucial for the integrity of muscle cells, are the root cause of this genetic condition. Muscle fibers are more easily injured…
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Introduction: A chromosome (trisomy 21) that is present in its entirety or in part results in the genetic condition known as Down syndrome (trisomy 21). The majority of patients have mild to severe intellectual disability, growth retardation, and distinctive facial traits when they first present. Down syndrome can influence a person’s mental capacity and physical development, lead to a variety of developmental differences, and increase their chance of developing certain health issues. Most people with Down syndrome have an extra copy of chromosome 21. A number of screenings can be used by medical experts to identify Down syndrome. The three…
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INTRODUCTION: The thyroid is a small, butterfly-shaped gland located at the front of the neck and controlled by the pituitary gland. Thyroid hormones play a vital role in the human body; hence, if the range of thyroid hormones fluctuates, it will cause many diseases like hypothyroidism and hyperthyroidism. In hypothyroidism, the level of thyroid decreases in the blood, which is a clinical syndrome characterized by a low metabolic state due to the low serum thyroid in the blood. Hypothyroidism is the most frequent clinical illness caused by thyroid hormone insufficiency and, if ignored, can result in major adverse health effects…
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INtroduction Diphtheria is a bacterial illness that has traditionally been a major public health concern, producing severe respiratory and systemic consequences. This extremely infectious disease, caused by Corynebacterium diphtheria, predominantly affects the respiratory tract and can result in the production of a thick grayish-white membrane in the throat, restricting breathing and swallowing. Diphtheria has been the target of extensive medical research and public health initiatives, which have resulted in the development of effective vaccinations that have significantly decreased its prevalence and impact in many areas of the world. Diphtheria’s history is linked with the evolution of vaccination methods. Diphtheria was…
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Introduction: Diabetes is a chronic disease characterized by the pancreas’s insufficient insulin production. Insulin, a hormone, regulates blood sugar levels. Uncontrolled diabetes frequently results in hyperglycemia, also known as high blood glucose or elevated blood sugar, which can affect a variety of body systems, including neurons and blood vessels, over time. A glucose metabolic disorder characterized by the body’s impaired ability to produce or respond to insulin. As a result, keep healthy levels of sugar (glucose) in your blood. People with this disease typically have a high level of glucose in their blood, which can lead to a variety of…
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introduction Cushing’s syndrome, is a rare and complicated medical illness caused by extended exposure to elevated cortisol levels in the body. This illness can have a variety of severe impacts on numerous internal systems, resulting in a slew of symptoms and problems. Cushing’s syndrome, named after the renowned neurosurgeon Harvey Cushing, who first described it in the early twentieth century, can be caused by a variety of factors, including adrenal gland overproduction of cortisol, excessive use of corticosteroid medications, or tumors that produce cortisol. Cushing’s syndrome presents with a wide range of symptoms, making it a difficult illness to identify…
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Introduction: Crohn’s disease is an inflammatory bowel illness that causes chronic inflammation of the gastrointestinal tract. Several reasons behind this, including a dysregulated immune system, altered microbiota, genetic vulnerability, and environmental factors, have been linked to the origin of Crohn’s disease. The cause of the disease remains unexplained. In most cases, the disease’s development at a young age demands immediate but long-term treatment to prevent disease flares and disease progression with intestinal consequences. Thus, early treatment with medicines or innovative small molecules could significantly alter the disease’s natural history, reducing complications and the need for hospitalization and surgery. Crohn’s disease…
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INTRODUCTION: People usually feel abdominal pain and acidity and take over-the-counter medications to suppress the symptoms. Do they do it right? The inflammatory disease that affects the rectum and colon can be called colitis. Colitis patients have mucosal inflammation that starts in the rectum and can extend to other areas of the gut, like the colon. The symptoms of this deadly disease are diarrhea, which can be diagnosed by colonoscopy. This disease affects those who have a family history of colitis, which means that genetics plays a role here, but along with this, some environmental factors can also cause it.…