Introduction Blood transfusions are essential in modern medical practice, providing major support in various clinical situations, including surgeries, trauma care, and treatment of blood disorders. Despite the life-saving potential of blood transfusions, they carry risks, particularly when the donor and recipient blood is incompatible. One of the most serious complications is an acute hemolytic reaction (AHR). Understanding this condition, its causes, symptoms, associated risks, and management strategies is vital for healthcare professionals to prevent and treat these potentially life-threatening reactions effectively.   What is an Acute Hemolytic Reaction? An Acute Hemolytic Reaction (AHR) occurs when the recipient’s immune system rapidly…