INTRODUCTION: Amyotrophic lateral sclerosis (ALS) was originally defined as a pure motor neuron disease by Jean-Martin Charcot in 1869 but is now recognized as a multisystem neurodegenerative disorder, with disease heterogeneity at the clinical, genetic, and neuropathological level. We walk, we run, and we do exercises like aerobics, physical exercise, or yoga. All these are voluntary movements. What is a voluntary moment? The movements that we asked our brain to do What if we have no control over our voluntary movements? What if you want to raise your hand but your hand won’t be able to conduct your command? All…