Introduction Systemic lupus erythematosus (SLE), commonly known as lupus, is a chronic autoimmune disease that can affect multiple organs and systems in the body. Its unpredictable nature—with periods of flares and remission—makes treatment complex. While there is no cure for lupus, significant progress has been made in managing the disease through medications that reduce inflammation, suppress the immune system, and prevent organ damage. From time-tested treatments like hydroxychloroquine to newer biologic therapies, medications play a vital role in controlling symptoms, improving quality of life, and preventing long-term complications. This article explores the most commonly used drugs in lupus treatment, their…