Introduction: Malignant brain tumors, including glioblastoma multiforme (GBM), present significant challenges in terms of treatment due to their invasive nature and resistance to conventional therapies. Recent research has shed light on ferroptosis. A form of regulated cell death characterized by iron-dependent lipid peroxidation, as a potential mechanism underlying the pathogenesis of these tumors. The role of ferroptosis in malignant brain tumors and its regulation could offer novel therapeutic avenues for combating these aggressive cancers. Let’s discuss the emerging field of ferroptosis in brain tumors, exploring its mechanisms, regulatory pathways, and potential therapeutic strategies. The Role of Ferroptosis in Malignant…