Introduction Lyme disease, caused by the bacterium Borrelia burgdorferi and transmitted by ticks, is the most common vector-borne illness in North America and Europe. While many people recover fully after appropriate antibiotic treatment, a subset continues to experience lingering symptoms. This has led to the controversial and widely debated concept of Chronic Lyme Disease (CLD) or Post-Treatment Lyme Disease Syndrome (PTLDS). This article breaks down what Chronic Lyme Disease is, why it’s controversial, the difference between PTLDS and CLD, perspectives from both sides of the debate, and what patients should know about treatment and support. What Is Lyme Disease? (Quick…