Introduction Acetaminophen, also known as paracetamol in many countries, is one of the most widely used over-the-counter (OTC) medications for pain relief and fever reduction. Found in countless household medicine cabinets, its widespread availability and perceived safety often overshadow the potential dangers it can pose—particularly when taken in excess. One of the most insidious ways an acetaminophen overdose can occur is through the use of multi-symptom cold and flu medications, which frequently contain acetaminophen alongside other ingredients such as decongestants, cough suppressants, and antihistamines. Consumers, often unaware that they are ingesting the same active ingredient from multiple sources, can inadvertently…