Introduction Nonsteroidal anti-inflammatory drugs (NSAIDs) are commonly prescribed for pain management, inflammation, and fever reduction. These drugs, including ibuprofen, naproxen, and aspirin, are often used to treat a wide variety of conditions, from arthritis to acute injuries. However, when used in combination with other medications, particularly those affecting the cardiovascular system, there can be serious interactions that require careful monitoring. One such interaction is between NSAIDs and digoxin, a cardiac glycoside commonly used to treat heart failure and atrial fibrillation. Digoxin works by increasing the force of heart contractions and regulating heart rate, improving symptoms of heart failure and controlling…