Introduction: Administering medication to neonates presents unique challenges due to their physiological immaturity and sensitivity to drugs. Ensuring medication safety and accurate dosage is crucial for this vulnerable population. This article explores the principles of neonatal medication safety, safe administration practices, and dosage considerations.   Neonatal Medication Safety Neonates, defined as infants less than 28 days old, have distinct physiological characteristics that necessitate special attention when prescribing and administering medications. Factors such as underdeveloped organ systems, rapid growth, and limited ability to metabolize drugs can significantly influence neonatal medication safety.   Key Principles of Neonatal Medication Safety Precision: Accurate dosing…