Introduction: A genetic condition known as Huntington’s disease (HD) causes the neurons in some areas of the brain to slowly degenerate and die. Huntington’s disease (HD), a brain disorder that affects the entire body and is caused by a dominantly inherited amplification of the CAG trinucleotide repeat in the Huntington’s gene on chromosome The illness targets different parts of the brain, including those involved in the regulation of voluntary (intentional) movement. Individuals with Huntington’s disease (HD) experience strange body postures, involuntary dance-like movements (chorea), and behavioural, emotional, cognitive, and personality issues. People with a history of this disease are more…
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Introduction: When the genes in your body are affected by a mutation—a negative change to a gene also known as a pathogenic variant—or when you have an improper amount of genetic material, genetic illnesses can develop. DNA (deoxyribonucleic acid), which makes up genes, contains instructions for how cells should function as well as the traits that distinguish people from one another. Each biological parent provides you with half of your DNA, and you may inherit a gene mutation from one or both of your parents. Genes can occasionally change as a result of problems with the DNA (mutations). Your chance…
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Introduction: A chromosome (trisomy 21) that is present in its entirety or in part results in the genetic condition known as Down syndrome (trisomy 21). The majority of patients have mild to severe intellectual disability, growth retardation, and distinctive facial traits when they first present. Down syndrome can influence a person’s mental capacity and physical development, lead to a variety of developmental differences, and increase their chance of developing certain health issues. Most people with Down syndrome have an extra copy of chromosome 21. A number of screenings can be used by medical experts to identify Down syndrome. The three…