Introduction Lupus, or systemic lupus erythematosus (SLE), is an autoimmune disease in which the immune system attacks healthy tissues throughout the body. Among its most serious complications is lupus nephritis, a form of kidney inflammation caused by lupus. The kidneys play a crucial role in filtering waste and maintaining fluid balance. When lupus affects the kidneys, it can lead to significant damage, kidney failure, or even life-threatening complications if not properly managed. Understanding lupus nephritis—how to detect it, monitor its progression, and treat it effectively—is essential for patients and healthcare providers alike. This article explores the connection between lupus and…