Introduction Macroglobulinemia is a rare blood disorder characterized by the overproduction of an abnormal protein known as macroglobulin. Furthermore, This condition can lead to various complications, including impaired blood flow and then damage to multiple organs. Moreover, Understanding macroglobulinemia, its causes, symptoms, and then treatment options is essential for managing this complex disease and improving patient outcomes. What is Macroglobulinemia? Macroglobulinemia is a type of monoclonal gammopathy in which a single clone of plasma cells produces large amounts of a specific immunoglobulin or antibody. Moreover, The most common form is Waldenström macroglobulinemia (WM), which involves the overproduction of immunoglobulin…