Introduction Migraines are a debilitating neurological condition affecting millions worldwide, often characterized by intense, throbbing headaches accompanied by nausea, light sensitivity, and other symptoms. For many sufferers, managing migraine pain effectively is a critical daily challenge. Over-the-counter (OTC) medications provide accessible relief options, but the market is increasingly divided between migraine-specific formulations and generic alternatives. This article explores the differences between these options, focusing on their ingredients, clinical efficacy, costs, and how patients can personalize their migraine management. Active Ingredient Combinations in Migraine Formulas Migraine-specific OTC products typically contain a carefully selected combination of active ingredients designed to target the…