Introduction Nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen, naproxen, and aspirin are among the most commonly used over-the-counter (OTC) pain relievers worldwide. Their ability to reduce pain, inflammation, and fever makes them a go-to option for millions dealing with headaches, muscle aches, arthritis, and other ailments. However, while generally safe when taken as directed, high doses or prolonged use of NSAIDs can silently damage vital organs—especially the liver and kidneys. This article sheds light on the mechanisms behind NSAID-induced organ damage, explores cumulative dose thresholds and risk factors, identifies early warning signs of liver and kidney dysfunction, highlights populations at…
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Introduction Over-the-counter (OTC) cough medications are commonly found in medicine cabinets across America. While they offer relief for cold and flu symptoms, some contain dextromethorphan (DXM)—a cough suppressant that, in large doses, can produce psychoactive effects. This misuse, often referred to as “robotripping” or “skittling,” has emerged as a serious public health concern, particularly among teenagers seeking a cheap, accessible high. To address this issue, public health officials, educators, and lawmakers have increasingly turned to age restrictions and community education as preventive tools. But despite growing awareness, many parents and retailers remain unaware of the dangers DXM poses when abused,…
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Introduction For decades, phenylephrine has been a common ingredient in over-the-counter (OTC) cold and allergy medications marketed as effective nasal decongestants. Found in popular brands like Sudafed PE, DayQuil, and Tylenol Sinus, oral phenylephrine was widely assumed to relieve nasal congestion by shrinking blood vessels in the nasal passages. However, in a dramatic turn of events, experts from the U.S. Food and Drug Administration (FDA) have declared that oral phenylephrine is ineffective when taken at the recommended dose. This revelation has sparked national attention, consumer confusion, and calls for reform in how cold medications are regulated. The FDA’s Nonprescription Drugs…
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Introduction Caffeine is one of the most widely consumed stimulants in the world. Found naturally in coffee, tea, and chocolate—and added to sodas, energy drinks, and dietary supplements—it helps people stay alert, boost performance, and fight fatigue. However, caffeine is also a common ingredient in many over-the-counter (OTC) pain relievers, particularly those aimed at treating headaches, migraines, and menstrual cramps. While caffeine in moderation is generally safe, unintentional overconsumption can lead to serious health risks, especially when multiple sources are combined. A person who takes an OTC pain medication for a headache and later drinks an energy beverage or uses…