Introduction Hiccups are usually short-lived and harmless, resolving without any treatment. However, when hiccups persist for more than 48 hours (persistent hiccups) or even longer than 2 months (intractable hiccups), they can significantly disrupt eating, sleeping, and overall well-being. Persistent hiccups often indicate an underlying medical condition and may require professional medical interventions. This article explores the medical approaches used to evaluate and manage persistent hiccups, including diagnostic steps, medications, and more advanced treatments. Step 1: Medical Evaluation Before treating hiccups, doctors aim to identify the underlying cause. A thorough evaluation may include: Once the cause is determined, treatment focuses…