Introduction Monkeypox, a viral zoonotic disease, has seen a resurgence in recent years, affecting regions beyond its traditional endemic areas in Central and West Africa. While monkeypox is generally less severe than its cousin smallpox, it can still cause significant discomfort and complications. Effective treatment options are crucial for managing the disease, alleviating symptoms, and preventing severe outcomes. Moreover, This article explores the available treatment options for monkeypox, including antiviral medications, supportive care, and management strategies to address this emerging health concern.   Antiviral Medications Tecovirimat (TPOXX): Overview: Tecovirimat is an antiviral medication specifically developed for the treatment of orthopoxvirus…