Introduction: Cancer progression is a dynamic interplay between tumor cells and the host microenvironment, driven by a complex array of molecular and cellular interactions. Among the pivotal factors shaping cancer evolution are tumor mutations, immune evasion mechanisms, and the emergence of resistance to targeted therapies. Furthermore, Understanding the intricate crosstalk between these factors is paramount for unraveling the mechanisms underlying cancer progression and devising effective therapeutic strategies. Moreover, This blog will discuss the multifaceted relationships between tumor mutations, immune evasion, and then targeted therapy resistance, shedding light on their interconnected roles in driving cancer progression.   Tumor Mutations: Seeds of…